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Suspect histoplasmosis in returning travellers from an endemic area presenting with fever and cough

Histoplasmosis can present in a variety of ways, making it difficult to diagnose. Dr Staffolani and colleagues carried out a systematic review of 835 cases of histoplasmosis (including 45 clusters) from the literature, among immunocompetent patients who had recently returned from an endemic area. Manifestations included fever (91%), cough (55%), constitutional symptoms (58%), headache (52%) and chest pain (41%).

Candida auris found among Russian ICU patients

Dr Barantsevich and colleagues describe a series of 49 trauma patients at an ICU in Moscow from whom Candida auris was isolated. Fluconazole resistance was widespread. However, no isolates were recovered by monthly swabbing of the hospital environment, healthcare workers’ hands and devices.

LDBio rapid Aspergillus IgG test sensitive and specific for CPA

Lateral flow rapid diagnostics are sorely needed for many fungal infections. Scientists at the University of Manchester evaluated LDBio’s Aspergillus IgG test on patients at the National Aspergillosis Centre (UK). Compared to existing diagnostics, this test was more sensitive (91.6%) and more specific (98.0%) for chronic pulmonary aspergillosis

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