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How to minimise risk of mucormycosis in hospital linens

Healthcare linens (HCLs) have often been thought to contain Mucorales spores, which present a health hazard for those with compromised immune systems. Mucorales are widely distributed in the environment, including in soil, vegetation and compost, and spores are easily aerosolised and dispersed, so healthcare providers need to remain vigilant to ensure that these pathogens are […]

Length of treatment regime in chronic pulmonary aspergillosis (CPA)

One of the key questions when treating CPA is optimal length of drug regimens. New research is challenging established views of treatment length. CPA is an uncommon and problematic pulmonary disease, complicating many other respiratory disorders, thought to affect over three million people globally. The most common form of CPA is chronic cavitary pulmonary aspergillosis […]

Histoplasmosis in Guatemala – the danger of under-estimating fungal infections

Histoplasmosis is recognised as a major complication in those with HIV, even when receiving anti-retroviral treatment, but exact rates for this infection have been unclear.  A new study carried out by Narda Medina and colleagues has shown that histoplasmosis is more prevalent than originally thought. Their screening programme in Guatemala demonstrated overall histoplasmosis incidence in […]

Indonesian study shows link between fungal infections and tuberculosis (TB), with global implications

Tuberculosis is a debilitating respiratory disease that the World Health Organization estimates kills 1.5 million people annually. Worldwide, TB is the 13th leading cause of death. Although TB is treatable, this new Indonesian case study highlights the dangers of not having a laboratory-confirmed diagnosis, as suspected TB could be masking chronic pulmonary aspergillosis (CPA). TB […]

New PCR test developed to identify Coccidioidomycosis agents

A joint study between New York State Department Mycology Laboratory and the Department of Medical Mycology at the University of California has developed a new PCR test with the ability to detect and differentiate between Coccidioides immitis and C. posadasii. Coccidioidomycosis is often referred to as ‘valley fever’ and the fungus Coccidioides grows in soils in areas of low […]

Largest study of COVID-19-associated mucormycosis in India

A panel of 97 clinicians working in India have just released an expedited study looking at 2986 cases of COVID-19-associated rhino-orbital-cerebral mucormycosis (ROCM). This disease has reached epidemic proportion during India’s second wave of the COVID-19 pandemic and this large-scale study provides important insights into the pathogenesis and treatment of ROCM. This paper outlines the […]

Post-TB chronic pulmonary aspergillosis – global case studies

Tuberculosis (TB) is the leading cause of death from a single infectious agent worldwide. The highest burden is found in Africa and Asia – mostly linked to the human immunodeficiency virus (HIV) epidemic in these regions. The 2020 World Health Organization (WHO) TB report showed that globally in 2019, 10 million people developed this disease. […]

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