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Largest study of COVID-19-associated mucormycosis in India

A panel of 97 clinicians working in India have just released an expedited study looking at 2986 cases of COVID-19-associated rhino-orbital-cerebral mucormycosis (ROCM). This disease has reached epidemic proportion during India’s second wave of the COVID-19 pandemic and this large-scale study provides important insights into the pathogenesis and treatment of ROCM. This paper outlines the […]

Post-TB chronic pulmonary aspergillosis – global case studies

Tuberculosis (TB) is the leading cause of death from a single infectious agent worldwide. The highest burden is found in Africa and Asia – mostly linked to the human immunodeficiency virus (HIV) epidemic in these regions. The 2020 World Health Organization (WHO) TB report showed that globally in 2019, 10 million people developed this disease. […]

Histoplasmosis in the United States – new insights and myth busting

A new study carried out by the Mycotic Diseases Branch at the Centers for Disease Control and Prevention in Atlanta, Georgia, US is dispelling some of the common myths around histoplasmosis in the US. Previous research has theorised that histoplasmosis is the most common endemic mycosis in the United States and that its distribution is […]

Retrospective study aims to quantify global burden of chromoblastomycosis

Chromoblastomycosis (CBM) is classed as a Neglected Tropical Disease and the global burden for this infection has never before been classified. This new study considers published literature from 1914 to 2020. Over this period, a total of 7,740 patients with CBM were identified on all continents except Antarctica. Of these cases the authors identified 4,022 […]

Reports of echinocandin-resistant Candida auris in healthcare settings

The Centers for Disease Control is calling Candida auris a ‘global emerging threat’.  Pan-resistant C. auris isolates have been reported previously, although rarely, from the United States. Echinocandins are critical for treatment of C. auris infections and are recommended as first-line therapy for most invasive Candida infections, but the Antibiotic Resistance Laboratory Network has detected independent clusters of pan-resistant or echinocandin-resistant […]

Antifungal agents in biopolymer hydrogel wound dressing

A team from Wolverhampton, UK and Zabrze, Poland have made some interesting discoveries when using hydrogel as a method to administer antifungals within wound dressings. Wounds from various sources that have been in a prolonged state of irritation and rubor, with a high degree of exudate, are decidedly prone to becoming infected by various opportunistic […]

COVID-19 reverses gains in survival rates of HIV patients

Guatemala’s leading HIV centre reported that deaths from HIV rose from 16.6% to 27.3% during COVID-19. Just published in the International Journal of Infectious Diseases – Narda Medina and colleagues charted the provision of HIV care in Guatemala and how the global pandemic has affected diagnosis and treatment. Patient attendances and rapid services were also […]

Turkish review of mucormycosis in children shows high mortality rate and importance of urgent evaluation when infection is suspected

A new paper published by the Çukurova University Faculty of Medicine in Adana, Turkey, re-examines historical cases of mucormycosis in children. Mucormycosis is an emerging fungal infection with poor health outcomes. This infection is of particular interest due to its links to increased fatalities in the COVID-19 outbreak in India. This retrospective review focuses on […]

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