Our lecture series for clinicians focuses on the practical aspects of diagnosing and treating patients with fungal conditions. Featuring experts from around the world, they are illustrated with many clinical photographs and evidence from the scientific literature.
You can watch the lectures on our YouTube channel or download the slides and audio to use offline later. Then test yourself with our Twitter-based multiple choice questions. You may also find it useful to watch our diagnostics videos as they explain how the laboratory tests work and how to interpret the results.
If you would like to use these materials to run a course but do not have a sufficiently fast Internet connection to stream the lectures via YouTube, please email us and we can arrange to send a copy of the materials on a memory stick.
Antifungals
Voriconazole
Itraconazole
Flucytosine
Fluconazole
Antifungals and pregnancy/breastfeeding
Amphotericin B
CPIC guideline for Voriconazole and CYP2C19
TDM of azoles
TDM of flucytosine
Therapeutic drug monitoring of antifungals (webinar + Q&A): voriconazole, itraconazole, flucytosine
Updates on newer antifungal agents – Dr Atul Patel
| Voriconazole Prof David Denning | Slides (16:9 or 4:3) Audio only (MP3) |
| Itraconazole Prof David Denning | Slides (16:9 or 4:3) Audio only (MP3) |
| Fluconazole Dr Paschalis Vergidis | Slides (16:9 or 4:3) Audio only (MP3) |
| Flucytosine Dr Felix Bongomin | Slides (16:9 or 4:3) Audio only (MP3) |
| Amphotericin B Professor Pippa Newton | Slides (16:9 or 4:3) Audio only (MP3) |
| Antifungal therapy in pregnancy and breastfeeding Dr Felix Bongomin | Slides (16:9 or 4:3) Audio only (MP3) |
| Therapeutic drug monitoring (TDM) of azoles Dr Chris Kosmidis | Slides (16:9 or 4:3) Audio only (MP3) |
| Therapeutic drug monitoring (TDM) of flucytosine Prof David Denning | Slides (16:9 or 4:3) Audio only (MP3) |
CPA & ABPA
Surgical management of chronic pulmonary aspergillosis (CPA)
Chronic pulmonary aspergillosis: global burden and diagnosis
Managing chronic pulmonary aspergillosis (CPA)
ABPA management
| CPA global burden & diagnosis Dr Iain Page | Slides (16:9 or 4:3) Audio only (MP3) |
| CPA medical management Dr Chris Kosmidis | Slides (16:9 or 4:3) Audio only (MP3) |
| CPA surgery Dr Paschalis Vergidis | Slides (16:9 or 4:3) Audio only (MP3) |
| ABPA management Dr Rajesh Shah | Slides (16:9 or 4:3) Audio only (MP3) |
CPA
- Nonga (2018) CPA surgery
- Hayes and Novak-Frazer (2016) CPA: where are we, and where are we going?
- Bongomin et al (2018) 12-month outcomes
- Farid et al (2013) Surgery, antifungal therapy and risk of recurrence
- Naito et al (2018) Prognosis of CPA with NTM-LD
- Al-shair et al (2013) Long-term antifungal treatment
- Denning et al (2003) Case series
ABPA
- Agarwal et al (2007) Hyperattenuating mucoid impaction in ABPA
- Agarwal et al (2010) ABPA classification based on high-attenuating mucus
- Denning et al (2014) Fungal allergy in asthma
- Moss et al (2012) Biological agents for fungal asthma and ABPA
Cryptococcal meningitis
Cryptococcus mycology and virulence
Epidemiology of cryptococcosis
Diagnosing cryptococcal meningitis
Cryptococcal meningitis: pathogenesis and host response
Lumbar puncture in cryptococcal meningitis
Cryptococcal IRIS
Cryptococcal meningitis: treating with antifungals
Cryptoccal meningitis: treatment outcomes
Raised intracranial pressure in cryptococcosis
Cryptococcal antigen (CrAg) testing – Biosynex CryptoPS
Interpreting CrAg titres
Cryptococcal antigen (CrAg) testing (Dynamiker lateral flow device)
CrAg FungiXpert LFA (Era Biology)
IDIM: One World One Guideline – Cryptococcosis Methods Tutorial
| Mycology and virulence Prof Malcolm Richardson | Slides (16:9 or 4:3) Audio only (MP3) |
| Epidemiology Prof Malcolm Richardson | Slides (16:9 or 4:3) Audio only (MP3) |
| Clinical presentation Prof David Denning | Slides (16:9 or 4:3) Audio only (MP3) |
| Diagnosis Prof Malcolm Richardson | Slides (16:9 or 4:3) Audio only (MP3) |
| CrAg titre Dr Radha Rajasingham | Slides (16:9 or 4:3) Audio only (MP3) |
| Pathogenesis Dr Tihana Bicanic | Slides (16:9 or 4:3) Audio only (MP3) |
| Lumbar puncture Dr Neil Stone | Slides (16:9 or 4:3) Audio only (MP3) |
| Immune reconstitution inflammatory syndrome (IRIS) Dr Tihana Bicanic | Slides (16:9 or 4:3) Audio only (MP3) |
| Antifungal management Prof Thomas Harrison | Slides (16:9 or 4:3) Audio only (MP3) |
| Treatment outcomes Dr. Silé Molloy | Slides (16:9 or 4:3) Audio only (MP3) |
| Management of raised intracranial pressure Prof David Denning | Slides (16:9 or 4:3) Audio only (MP3) |
- Rajasingham et al. (2017) Global burden of HIV-associated crypto meningitis
- Hull & Heitman (2002) Genetics of C. neoformans
- Williamson et al. (2017) Epidemiology, immunology, diagnosis and therapy
- Mfinanga et al. (2015) Screening and community-based adherence support in people with advanced HIV
- Lofgren et al. (2017) Recent advances in treatment in resource-limited settings
- Haddow et al. (2010) Cryptococcal IRIS case definitions
- Beardsley et al (2016) CryptoDex trial – adjunctive dexamethasone
- Boulware et al (2014) COAT trial – timing of ARV after diagnosis of crypto meningitis
- Day et al (2013) Combination antifungal therapy (RCT)
- Kwon-Chung et al (2014) C. neoformans and C. gatti (review)
- Molloy et al (2018) ACTA trial – combination antifungal therapy in Africa
- Mourad and Perfect (2018) Present and future treatment
- Rolfes et al (2014) Effect of therapeutic lumbar puncture on mortality rates
- Mourad and Perfect (2018) Drug pipeline for cryptococcal disease
Candida
Candida diaper dermatitis (part 2/3)
Intra-abdominal candidiasis
Oesophageal Candida
Ep.1 Candida auris: A Resistant Fungal Infection | Medscape TV
Beta-D-glucan (Goldstream kit, Era Biology)
IDIM: EQUAL Scores – Candidiasis
Candida Endocarditis after TAVR
Beta-D-glucan (webinar + Q&A) fungal diagnostics – invasive Aspergillus Pneumocystis Candida
Candida albicans microbiology – microscopic examination,cuture(laboratory diagnosis)
| Invasive candidiasis Dr Arnaldo Lopes Colombo | Slides (16:9 or 4:3) Audio only (MP3) |
| Oesophageal candidiasis Dr. Riina Rautemaa-Richardson | Slides (16:9 or 4:3) Audio only (MP3) |
| Intra-abdominal candidiasis Dr Paschalis Vergidis | Slides (16:9 or 4:3) Audio only (MP3) |
| Oropharyngeal candidiasis Dr. Riina Rautemaa-Richardson | Slides (16:9 or 4:3) Audio only (MP3) |
| Diaper dermatitis Dr Immaculate Kariuki | Slides (16:9 or 4:3) Audio only (MP3) |
Invasive candidiasis:
- Lamoth et al (2018) Epidemiological landscape of invasive candidiasis
- Pea and Lewis (2018) Antifungal dosing in invasive candidiasis (review)
- Bassetti et al (2019) Treatment of invasive candidiasis (review)
Oesophagel and oropharyngeal:
- Vasquez (2010) Management of oropharyngeal and oesophageal candidiasis in patient with HIV
- Takahashi et al (2015) Prevalence and risk factors for oesophageal candidiasis
- Nishimura et al (2013) Risk factors for esophageal candidiasis in patients with HIV
- Choi et al (2012) Prevalence and risk factors for oesophageal candidiasis in non-HIV patients
Intra-abdominal:
- Bassetti et al (2013) Management of intra-abdominal candidiasis
- Azim et al (2017) Intra-abdominal candidiasis (review)
- Vergidis et al (2016) Early source control and antifungal treatment of intra-abdominal candidiasis
- Montravers et al (2013) Intra-abdominal candidiasis (review)
- Kullberg and Arendrup (2015) Invasive candidiasis (review)
Pneumocystis pneumonia
Assessing hypoxaemia in Pneumocystis patients
Pneumocystis microscopy
Pneumocystis management in children
Pneumocystis presentation in children
Prophylaxis for Pneumocystis
Pneumocystis coinfections
Beta-D-glucan testing (Dynamiker kit)
Beta-D-glucan testing (Fungitell kit)
Beta-D-glucan (Goldstream kit, Era Biology)
Beta-D-glucan (webinar + Q&A) fungal diagnostics – invasive Aspergillus Pneumocystis Candida
| Transmission & epidemiology Prof David Denning | Slides (16:9 or 4:3) Audio only (MP3) |
| Prophylaxis Dr Immaculate Kariuki | Slides (16:9 or 4:3) Audio only (MP3) |
| Presentation in children Dr Immaculate Kariuki | Slides (16:9 or 4:3) Audio only (MP3) |
| Management in children Dr Akaninyene Otu | Slides (16:9 or 4:3) Audio only (MP3) |
| Management in adults Dr Akaninyene Otu | Slides (16:9 or 4:3) Audio only (MP3) |
| Assessment of hypoxaemia Dr Immaculate Kariuki | Slides (16:9 or 4:3) Audio only (MP3) |
| Microscopy | Slides (16:9 or 4:3) Audio only (MP3) |
| Co-infections Dr Immaculate Kariuki | Slides (16:9 or 4:3) Audio only (MP3) |
Skin, hair & nails
Tinea capitis (part 3/3)
Tinea capitis (part 1/2)
Tinea capitis (part 2/2)
Skin manifestation of IFIs – Prof Ruoyu Li
Identification of molds & dermatophytes – Dr Pei-Lun Sun
| Tinea capitis Dr Immaculate Kariuki | Slides ( or ) Audio only () |
Radiology
Radiology of chronic pulmonary aspergillosis
Miliary lung pattern – radiology clinical lecture (tuberculosis, fungal lung infections)
Imaging – Why is it important in IFIs diagnosis?
Imaging for diagnosis of IFIs by Dr Tan
Radiology – ABPA